The protein LJM 111 from Lutzomyia longipalpis Salivary Gland Extract (SGE) accounts for the SGE-inhibitory effects upon inflammatory parameters in experimental arthritis model

► The salivary gland extract (SGE) inhibits neutrophil chemotaxis in a GRK-dependent downregulation of CXCR2 expression. ► The SGE modulates dendritic cells function and maturation. ► The LJM 111 protein modulates dendritic cells function and maturation.