کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5844099 1560953 2015 31 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Bivalirudin in stable angina and acute coronary syndromes
ترجمه فارسی عنوان
بایوالیریدین در آنژیوگرافی پایدار و سندرم حاد کرونری
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی داروشناسی
چکیده انگلیسی
A parenteral anticoagulant is indicated in patients with acute coronary syndromes. Which anticoagulant should be preferred in each setting is not clearly established. Bivalirudin administration was considered in acute coronary syndromes after several clinical trials showed decreased bleeding risk with its use compared with the association of unfractionated heparin (UFH) with glycoprotein IIb/IIIa inhibitors (GPIs). Most recent data demonstrate that the bleeding benefit identified in the previous studies was not due to bivalirudin's properties but to higher bleeding incidence in the comparator arm due to the disproportional use of GPIs with heparin. This paper reviews clinical evidence on bivalirudin as anticoagulant in stable angina and acute coronary syndromes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pharmacology & Therapeutics - Volume 152, August 2015, Pages 1-10
نویسندگان
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