کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5845742 | 1128307 | 2014 | 18 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Novel drug targets for asthma and COPD: Lessons learned from in vitro and in vivo models
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
پزشکی ریوی و تنفسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Novel drug targets for asthma and COPD: Lessons learned from in vitro and in vivo models Novel drug targets for asthma and COPD: Lessons learned from in vitro and in vivo models](/preview/png/5845742.png)
چکیده انگلیسی
Asthma and chronic obstructive pulmonary disease (COPD) are highly prevalent respiratory diseases characterized by airway inflammation, airway obstruction and airway hyperresponsiveness. Whilst current therapies, such as β-agonists and glucocorticoids, may be effective at reducing symptoms, they do not reduce disease progression. Thus, there is a need to identify new therapeutic targets. In this review, we summarize the potential of novel targets or tools, including anti-inflammatories, phosphodiesterase inhibitors, kinase inhibitors, transient receptor potential channels, vitamin D and protease inhibitors, for the treatment of asthma and COPD.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pulmonary Pharmacology & Therapeutics - Volume 29, Issue 2, December 2014, Pages 181-198
Journal: Pulmonary Pharmacology & Therapeutics - Volume 29, Issue 2, December 2014, Pages 181-198
نویسندگان
Katie E. Baker, Sara J. Bonvini, Chantal Donovan, Rachel E. Foong, Bing Han, Aruni Jha, Yasin Shaifta, Marieke Smit, Jill R. Johnson, Lyn M. Moir,