Mono-2-ethylhexyl phthalate induces oxidative stress responses in human placental cells in vitro

► MEHP increased reactive oxygen species, oxidative DNA damage, and caspase activity. ► MEHP induced expression of PTGS2, a gene important in pregnancy and parturition ► MEHP treatment resulted in differential expression of GLRX2, TXNRD1, and DHCR24.