In vitro toxic action potential of anti tuberculosis drugs and their combinations

- Anti-TB drugs Rifampicin (RIF), Isoniazid (INH) and Ethambutol (EMB) were tested.
- Drugs were tested alone and in combinations.
- RIF, individually, got significant dose dependent cytotoxic and mutagenic potential.
- Combination RIPE exhibited highly significant cytotoxic and mutagenic potential.
- Anti-TB drugs possess significant cytotoxic and mutagenic potential.