Corosolic acid induces apoptotic cell death in human lung adenocarcinoma A549 cells in vitro

► CRA inhibited A549 cells growth and induced apoptosis. ► CRA altered the expression of apoptosis-related proteins in A549 cells. ► CRA triggered mitochondria- and caspase-mediated apoptosis. ► ROS is involved in CRA-induced apoptosis.