Taurine ameliorate alloxan induced oxidative stress and intrinsic apoptotic pathway in the hepatic tissue of diabetic rats

► Diabetic hepatic dysfunction results from hyperglycemia and oxidative stress. ► Taurine, an antioxidant plays a beneficial role in organ pathophysiology. ► It augments intra-cellular antioxidant machineries and hepatic insulin signaling. ► It protects liver from mitochondrial dependent apoptosis. ► Taurine may act as a useful agent in hyperglycemia mediated liver dysfunction.