کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5854585 | 1561889 | 2015 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Comparisons of urinary phthalate metabolites and daily phthalate intakes among Japanese families
ترجمه فارسی عنوان
مقایسه متابولیت های فتالات ادرار و مصرف فتالات روزانه در میان خانواده های ژاپنی
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کلمات کلیدی
di-n-butyl phthalateDnBPBBzPDEHPMnBPmono-n-butyl phthalateMiBPNHANESISAACMWPdi-iso-nonyl phthalateMBzPRfDTDIMEHPMCNPMtBSTFAMECPPMEHHPMEOHPmono(2-ethyl-5-carboxypentyl) phthalateDBPEPALOQmCPPPCPDMPDIBPdibutyl phthalateBSTFADiNP - DINPGC/MS - GC / MSmono(2-ethyl-5-oxohexyl) phthalate - mono (2-ethyl-5-oxohexyl) phthalatemono(2-ethylhexyl) phthalate - mono (2-ethylhexyl) phthalateEnvironmental Protection Agency - آژانس حفاظت از محیط زیستNational Health and Nutrition Examination Survey - بررسی بهداشت و تغذیه ملیBenzyl butyl phthalate - بنزیل بوتیل فتالاتMono-benzyl phthalate - بنزیل فتالاتLOD یا Limit of detection - حد تشخیصReference dose - دوز مرجعdi(2-ethylhexyl) phthalate - دی (2-اتیل هگزیل) فتالاتdi-iso-butyl phthalate - دی ایزو بوتیل فتالاتdimethyl phthalate - دی متیل فتالاتSIM - سیم کارتPhthalate exposure - قرار گرفتن در معرض فتالاتPhthalate metabolites - متابولیت های فتالاتlimit of quantification - محدودیت اندازه گیریlimit of detection - محدودیت تشخیصpersonal care product - محصول مراقبت شخصیDaily intake - مصرف روزانهTolerable daily intake - مصرف روزانه قابل تحملmono-isobutyl phthalate - مونو ایزوبوتیل فتالاتCreatinine clearance rate - میزان ترخیص کراتینینbody weight - وزن بدنPVC - پلیوینیل کلراید یا پیویسیgas chromatography/mass spectrometry - کروماتوگرافی گاز / طیف سنج جرمیPolyvinyl chloride - کلرید پلی وینیلChildren - کودکان
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
بهداشت، سم شناسی و جهش زایی
چکیده انگلیسی
We measured urinary phthalate metabolites, including di-n-butyl phthalate (DnBP), di-isobutyl phthalate, benzyl butyl phthalate (BBzP), and di(2-ethylhexyl) phthalate (DEHP), from 178 school-aged children and their 284 family members using gas chromatography-mass spectrometry, and we calculated daily phthalate intakes. The highest median levels of phthalate metabolites were for mono-isobutyl phthalate in all participants except schoolchildren, where the highest levels were for mono-(2-ethyl-5-oxohexyl) phthalate (MEOHP). Comparing the schoolchildren with their parents, the schoolchildren had significantly higher urinary metabolites for MEOHP, mono-(2-ethyl-5-carboxypentyl) phthalate, and ΣDEHP. Regarding daily intakes, the schoolchildren had significantly higher daily intakes of DnBP, BBzP, and ΣDEHP. All phthalate metabolite and sums of metabolite levels in the schoolchildren were positively correlated with their mothers' levels, except for MEHP, whereas fathers were less correlated with their children. The DEHP intake in this study was higher than that of most other studies. Moreover, 10% of the children and 3% of the adults exceeded the Reference Dose (RfD) value (20 μg/kg/day) of the U.S. Environmental Protection Agency, which indicates that it is important to focus on children's DEHP exposure because the children exceeded the RfD more than adults among the same families who shared similar exposure sources. Our results will contribute to considerations of the regulations for some phthalates and the actual phthalate exposure levels in the Japanese population.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Hygiene and Environmental Health - Volume 218, Issue 5, July 2015, Pages 461-470
Journal: International Journal of Hygiene and Environmental Health - Volume 218, Issue 5, July 2015, Pages 461-470
نویسندگان
Yu Ait Bamai, Atsuko Araki, Toshio Kawai, Tazuru Tsuboi, Eiji Yoshioka, Ayako Kanazawa, Shi Cong, Reiko Kishi,