Effect of low-dose thalidomide on dopaminergic neuronal differentiation of human neural progenitor cells: A combined study of metabolomics and morphological analysis

► Thalidomide inhibited the dopaminergic neuronal differentiation of hNPCs. ► Thalidomide impaired thedopamine and methionine metabolic pathways. ► Thalidomide decreased the number of tyrosine hydroxylase-positive neurons. ► The CE-TOFMS-based metabolomics technique was applied.