کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5855746 | 1562122 | 2016 | 29 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
How accurately and consistently do laboratories measure workplace concentrations of respirable crystalline silica?
ترجمه فارسی عنوان
چگونه آزمایشگاه ها با دقت و پایدار، غلظت سیلیکا بلورین قابل انفجار را اندازه گیری می کنند؟
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
بهداشت، سم شناسی و جهش زایی
چکیده انگلیسی
Permissible exposure limits (PELs) for respirable crystalline silica (RCS) have recently been reduced from 0.10 to 0.05Â mg/m3. This raises an important question: do current laboratory practices and standards for assessing RCS concentrations permit reliable discrimination between workplaces that are in compliance and workplaces that are not? To find out, this paper examines recent laboratory performance in quantifying RCS amounts on filters sent to them to assess their proficiency. A key finding is that accredited laboratories do not reliably (e.g., with 95% confidence) estimate RCS quantities to within a factor of 2. Thus, laboratory findings indicating that RCS levels are above or below a PEL provide little confidence that this is true. The current accreditation standard only requires laboratories to achieve estimates within three standard deviations of the correct (reference) value at least two thirds of the time, rather than a more usual standard such as within 25% of the correct value at least 95% of the time. Laboratory practices may improve as the new PEL is implemented, but they are presently essentially powerless to discriminate among RCS levels over most of the range of values that have been tested, leaving employers and regulators without a reliable means to ascertain when workplace RCS levels are above or below the PEL.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Regulatory Toxicology and Pharmacology - Volume 81, November 2016, Pages 268-274
Journal: Regulatory Toxicology and Pharmacology - Volume 81, November 2016, Pages 268-274
نویسندگان
Louis Anthony (Tony) Jr.,