کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5856678 1131980 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Prescribing patterns of the four most commonly used sedatives in endoscopic examination in Korea: Propofol, midazolam, diazepam, and lorazepam
ترجمه فارسی عنوان
الگوهای تجویز چهار رژیم غذایی رایج در آزمایش اندوسکوپی در کره: پروپوفول، میدازولام، دیازپام و لورازپام
کلمات کلیدی
پروپوفول میدازولام، دیازپام، لورازپام، روحانیون، سو استفاده کردن، معاینه اندوسکوپی،
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست بهداشت، سم شناسی و جهش زایی
چکیده انگلیسی


- In this study, we analyzed the usage of four commonly used sedatives in endoscopic examination (propofol, midazolam, diazepam, and lorazepam).
- Midazolam was the most commonly used sedative.
- Propofol use doubled between 2008 and 2012.
- We identified several patient cases of suspected sedative abuse.

As the sedative use increases due to the effectiveness and relatively safe profile, the abuse potential is also increasing. This study was conducted to examine the usage of four sedative agents in endoscopic examination and to compare the propofol use with the other three sedatives. Using National Health Insurance claims data from 2008 to 2012, we identified the number of cases of conscious sedation during endoscopy using one or more of the following agents: propofol, midazolam, diazepam, and lorazepam. The general characteristics of patients and medical service providers were analyzed, and the regional and annual distributions of frequency of use were compared. We also identified patient cases with excessive number of endoscopic examinations. Among the total of 3,156,231 sedatives users, midazolam was the most commonly used agent (n = 2,845,250, 90.1%). However, the largest increase in patient number, which increased from 11,410 in 2008 to 28,170 in 2012, was observed with propofol. While the majority of patients received an annual endoscopy, we identified several suspected abuse cases of patients receiving endoscopies repetitively as many as 114 times in five years. The rise of sedative use in endoscopic examinations and several patient cases of repeated sedative administration suggest a potential risk for abuse. Medical service providers should be cautious when using sedatives and carefully review each patient's medical history prior to the procedure.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Regulatory Toxicology and Pharmacology - Volume 71, Issue 3, April 2015, Pages 565-570
نویسندگان
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