The threshold of toxicological concern for prenatal developmental toxicity in rabbits and a comparison to TTC values in rats

► Fifth percentile of 104 NOAELs of rabbit developmental tox studies is 2 mg/kg bw. ► A TTC value for rabbit developmental toxicity of 4 μg/kg bw/d was calculated. ► Rabbits are not overtly more sensitive for developmental toxicity than rats.