کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5858035 1562161 2015 22 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Embryo Form Project: An original technique for the three-dimensional reconstruction of human embryo morphology
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست بهداشت، سم شناسی و جهش زایی
پیش نمایش صفحه اول مقاله
Embryo Form Project: An original technique for the three-dimensional reconstruction of human embryo morphology
چکیده انگلیسی
Our current knowledge on the developmental stages of human embryogenesis has derived from limited numbers of classical studies. Computer technology now permits accurate 3D reconstruction of embryo morphology from serial histological sections. We present a successful technique that uses either fresh or preserved serial histological sections to generate highly detailed 3D image reconstructions of very small human embryos. We present the data we obtained from the reconstruction in virtual space of previously sectioned 15 and 22.5 mm embryos. Their morphologies were studied using a DICOM viewer which permitted the analysis of any specific structure in any required orientation. To our knowledge, this is the first time human embryos have been reconstructed in this way. We believe that this reconstruction technique could improve our knowledge on embryo morphogenesis, especially if coupled to the study of genes involved in embryonic development. It may also prove to be a useful pedagogical tool.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Reproductive Toxicology - Volume 58, December 2015, Pages 1-7
نویسندگان
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