کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5858839 1562170 2014 19 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Use of ovary culture techniques in reproductive toxicology
ترجمه فارسی عنوان
استفاده از تکنیک های کشت تخمدان در سم شناسی تولید مثل
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست بهداشت، سم شناسی و جهش زایی
چکیده انگلیسی
There is increasing evidence to indicate that a substantial number of both man-made and naturally occurring chemicals are disruptive to human and wildlife reproductive health. Currently, reproductive toxicology testing is primarily carried out in vivo, however, in the past 50 years, various culture methods have been developed with the aim of growing ovarian follicles in vitro. These culture systems have become a widely used tool in reproductive biology and toxicology. In this review we describe how reproductive toxicology of the ovary is greatly enhanced by in vitro studies. Experiments using in vitro ovarian cultures to understand or detect damage to the ovary itself and to its specialised structures of the follicles and oocytes, allows for faster screening of potential developmental and/or reproductive toxicants.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Reproductive Toxicology - Volume 49, November 2014, Pages 117-135
نویسندگان
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