کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5859828 1562628 2016 22 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Inflammatory mechanisms of pulmonary injury induced by mustards
ترجمه فارسی عنوان
مکانیسم التهابی آسیب های ریه ناشی از خردل
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست بهداشت، سم شناسی و جهش زایی
چکیده انگلیسی
Exposure of humans and animals to vesicants, including sulfur mustard (SM) and nitrogen mustard (NM), causes severe and debilitating damage to the respiratory tract. Both acute and long term pathological consequences are observed in the lung following a single exposure to these vesicants. Evidence from our laboratories and others suggest that macrophages and the inflammatory mediators they release play an important role in mustard-induced lung injury. In this paper, the pathogenic effects of SM and NM on the lung are reviewed, along with the potential role of inflammatory macrophages and mediators they release in mustard-induced pulmonary toxicity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Toxicology Letters - Volume 244, 26 February 2016, Pages 2-7
نویسندگان
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