New insights into the Ca2+-ATPases that contribute to cadmium tolerance in yeast

► Inactivation of the PMR1 gene in Saccharomyces cerevisiae delayed initial cadmium uptake. ► Cells lacking functional Pmr1p increased basal expression of PMC1 and YCF1 genes. ► Cadmium treatment altered the expression of yeast internal Calcium transporters. ► PMC1 expression is induced substantially by cadmium in wild-type yeast cells.