کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5861908 1133768 2015 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Does carbonation of steel slag particles reduce their toxicity? An in vitro approach
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست بهداشت، سم شناسی و جهش زایی
پیش نمایش صفحه اول مقاله
Does carbonation of steel slag particles reduce their toxicity? An in vitro approach
چکیده انگلیسی
LD slag had the higher Fe, Mn and V content, and was more cytotoxic than stainless steel slag. The cytotoxic activity of LD but not of stainless dusts was reduced after carbonation. The cytotoxic activity of the dusts toward J774 macrophages necessitated a direct contact with the cells and was reduced in the presence of inhibitors of phagocytosis (cytochalasin D) or phagolysosome acidification (bafilomycin), pointing to a key role of metallic constituents released in phagolysosomes. This in vitro study supports a limited reduction of the cytotoxic activity of LD, but not of stainless, steel dusts upon carbonation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Toxicology in Vitro - Volume 29, Issue 4, June 2015, Pages 722-726
نویسندگان
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