An evaluation on combination effects of phenolic endocrine disruptors by estrogen receptor binding assay

► Phenolics show a relative estrogenic potency of BPA > 4-t-OP > 4-NP > 2,4-DCP. ► Phenolic mixtures act as an antagonistic mode in estrogen receptor binding assay. ► 2,4-DCP shows a weak estrogenic potency.