A human hemi-cornea model for eye irritation testing: Quality control of production, reliability and predictive capacity

► We present the construction of a tissue engineered hemi-cornea model based on human cell lines. ► We show the reproducible construction of this model in independent laboratories. ► We have developed an in vitro test system for eye irritation testing based on this model. ► We present the predictive capacity of this system and the inter-laboratory reproducibility.