Penta-O-galloyl-β-d-glucose attenuates cisplatin-induced nephrotoxicity via reactive oxygen species reduction in renal epithelial cells and enhances antitumor activity in Caki-2 renal cancer cells

► PGG protects cisplatin-induced apoptosis in human renal epithelial cells. ► PGG impairs ROS production in cisplatin-treated human renal epithelial cells. ► PGG enhances cisplatin-induced apoptosis in Caki-2 kidney cancer cells.