کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5890187 1568153 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Original Full Length ArticleThe fracture sites of atypical femoral fractures are associated with the weight-bearing lower limb alignment
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شناسی تکاملی
پیش نمایش صفحه اول مقاله
Original Full Length ArticleThe fracture sites of atypical femoral fractures are associated with the weight-bearing lower limb alignment
چکیده انگلیسی


- We hypothesized that the patient's individual anatomical factor(s) were related to the fracture site of AFFs.
- The fracture site (FS) and standing femorotibial angle (FTA) in lower limb radiographs were investigated.
- The FS and FTA of patients with typical femoral fractures (TFF) were compared to those of patients with AFFs.
- The fracture sites of AFFs are associated with the standing FTA, while those of TFFs are not.

PurposeAtypical femoral fractures (AFFs) are stress-related fractures that are speculated to associate with long-term treatment with bisphosphonates for osteoporosis. A history of AFF is a high risk factor for the development of a subsequent AFF in the same location of the contralateral femur, suggesting that a patient's individual anatomical factor(s) are related to the fracture site of AFFs. In this study, we investigated the radiographs of fourteen AFFs (four bilateral fractures among ten patients) treated at six hospitals associated with our university between 2005 and 2010. The fracture site and standing femorotibial angle (FTA), which reflects the mechanical axis of the lower limb, were measured on weight-bearing lower limb radiographs. The fracture site and FTA of patients with typical femoral fractures (TFF) were compared to those of patients with AFFs. The correlations were examined using Spearman's rank correlation coefficients. The fracture locations in the femora were almost the same in the patients with bilateral AFFs. There was a positive correlation between the fracture site and the standing FTA in the patients with AFFs (r = 0.82, 95% confidence interval; 0.49 to 0.94), indicating that the larger the standing FTA (varus alignment), the more distal the site of the fracture in the femur. The FTA of the patients with atypical diaphyseal femoral fracture were significantly larger compared to that of those with not only atypical subtrochanteric fractures but also TFFs. In conclusion, the fracture sites of AFFs are associated with the standing lower limb alignment, while those of TFFs are not.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bone - Volume 66, September 2014, Pages 105-110
نویسندگان
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