کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5896478 1154957 2015 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Noncoding RNAs and the control of signalling via nuclear receptor regulation in health and disease
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
پیش نمایش صفحه اول مقاله
Noncoding RNAs and the control of signalling via nuclear receptor regulation in health and disease
چکیده انگلیسی
Nuclear receptors belong to a superfamily of proteins that play central roles in human biology, orchestrating a large variety of biological functions in both health and disease. Understanding the interactions and regulatory pathways of NRs will allow development of potential therapeutic interventions for a multitude of disease processes. Non-coding RNAs have recently been discovered to have significant interactions with NR signalling pathways via a variety of biological connections. This review summarises the known interactions between ncRNAs and the NR superfamily in health, embryogenesis and a plethora of human diseases.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Best Practice & Research Clinical Endocrinology & Metabolism - Volume 29, Issue 4, August 2015, Pages 529-543
نویسندگان
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