کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5898747 1568798 2016 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Glycemic control during consecutive days with prolonged walking exercise in individuals with type 1 diabetes mellitus
ترجمه فارسی عنوان
کنترل گلیسمی در طول روزهای متوالی با ورزش طولانی مدت در افراد مبتلا به دیابت نوع 1
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
چکیده انگلیسی


- Food intake, insulin administration, and 24-h glycemic control was monitored in individuals with type 1 diabetes participating in the world's largest walking event (4 walking days; daily distance 40 or 50 km).
- Despite large increments in energy- and carbohydrate intake, the daily insulin administration was reduced by 26% during the walking event.
- The large self-initiated adjustments in carbohydrate intake and insulin administration appeared to be sufficient to prevent an exercise-induced impairment in glycemic control.

AimsDespite its general benefits for health, exercise complicates the maintenance of stable blood glucose concentrations in individuals with type 1 diabetes. The aim of the current study was to examine changes in food intake, insulin administration, and 24-h glycemic control in response to consecutive days with prolonged walking exercise (∼8 h daily) in individuals with type 1 diabetes.MethodsTen individuals with type 1 diabetes participating in the worlds' largest walking event were recruited for this observational study. Simultaneous measurements of 24-h glycemic control (continuous glucose monitoring), insulin administration and food intake were performed during a non-walking day (control) and during three subsequent days with prolonged walking exercise (daily distance 40 or 50 km).ResultsDespite an increase in daily energy (31 ± 18%; p < 0.01) and carbohydrate (82 ± 71 g; p < 0.01) intake during walking days, subjects lowered their insulin administration by 26 ± 16% relative to the control day (p < 0.01). Average 24-h blood glucose concentrations, the prevalence of hyperglycemia (blood glucose >10 mmol/L) and hypoglycemia (blood glucose <3.9 mmol/L) did not differ between the control day and walking days (p > 0.05 for all variables). The prolonged walking exercise was associated with a modest increase in glycemic variability compared with the control day (p < 0.05).ConclusionProlonged walking exercise allows for profound reductions in daily insulin administration in persons with type 1 diabetes, despite large increments in energy and carbohydrate intake. When taking such adjustments into account, prolonged moderate-intensity exercise does not necessarily impair 24-h glycemic control.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diabetes Research and Clinical Practice - Volume 117, July 2016, Pages 74-81
نویسندگان
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