کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5908697 1570164 2016 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Research paperFirst genetic characterization of rotavirus C in Russia
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک بوم شناسی، تکامل، رفتار و سامانه شناسی
پیش نمایش صفحه اول مقاله
Research paperFirst genetic characterization of rotavirus C in Russia
چکیده انگلیسی


- This is the first report on genetic characterization of RVC in Russia.
- A total of 2144 stool samples collected during five years were analyzed.
- Eleven RVC strains were characterized and compared with strains from other countries.
- Circulating RVCs with at least two different genome backgrounds were found.

Rotaviruses C (RVC) cause sporadic cases and outbreaks of diarrhea in humans and animals worldwide. The aim of this study was to monitor RVC during a surveillance study of sporadic cases of viral gastroenteritis in the Novosibirsk and Omsk regions of Russia from 2006 to 2011. A total of 2144 stool samples from children and adults hospitalized with acute gastroenteritis were tested for RVC by RT-PCR. Sixteen RVC-positive stool samples were detected at a rate of 0.6% (13/2037) in children and 2.8% (3/107) in adults. The low detection rate suggested that RVC infection was an uncommon cause of hospitalization in Russia. The complete VP7, VP4, VP6, and NSP4 gene sequences were determined. It was found that RVCs with at least two different genome backgrounds circulated in Siberia. VP4, VP6, and NSP4 gene sequences of most Russian RVC strains clustered with South Asian strains, while the VP7 gene showed a closer relationship to European strains. Meanwhile, only VP4 and NSP4 sequences of the strain Omsk08-386 clustered with South Asian strains, while its VP6 and VP7 sequences clustered with European strains. This is the first genetic characterization of Russian RVC strains and the first report on the prevalence of RVC in the Asian part of Russia.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Infection, Genetics and Evolution - Volume 39, April 2016, Pages 1-8
نویسندگان
, , , , , ,