Mesoscale simulation on patterned core-shell nanosphere model for amphiphilic block copolymer

► In this study, nanospheres with perforate vesicle formed by ABA triblock copolymer, like carbon fullerene, were obtained at moderate ratio of hydrophilic and hydrophobic solvent blocks. ► Their morphological patterns are related to the polymer concentration, polymer-solvent interaction parameter and the diameter of the nanospheres. ► The approach reported in this work will furnish important and useful information to experiments of amphiphilic polymer nanospheres.