کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5949926 1172394 2011 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Testosterone and cardiovascular disease: An old idea with modern clinical implications
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Testosterone and cardiovascular disease: An old idea with modern clinical implications
چکیده انگلیسی

The role of sex steroid hormones in modulating vascular function in men is of great importance, given that androgen deficiency is strongly associated with common medical conditions including metabolic syndrome, obesity, diabetes, hypertension and atherosclerosis. Testosterone deficiency afflicts approximately 30% of men ages 40-79 years. Testosterone replacement in deficient men with such co-morbidities ameliorates or partially reverses their progression. Studies in animal and humans suggest that androgen deficiency is associated with increased triglycerides (TGs), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C). Emerging evidence indicates that androgens may provide a protective effect against the development and/or progression of atherosclerosis in men.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Atherosclerosis - Volume 214, Issue 2, February 2011, Pages 244-248
نویسندگان
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