کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5981759 1576995 2016 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Inflammation as a Driver of Adverse Left Ventricular Remodeling After Acute Myocardial Infarction
ترجمه فارسی عنوان
التهاب به عنوان یک راننده سمت چپ آسیب دیده؟ یک ترمیم بطن چپ پس از انفارکتوس حاد قلب
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی

Treatment of acute myocardial infarction (AMI) has improved significantly in recent years, but many patients have adverse left ventricular (LV) remodeling, a maladaptive change associated with progressive heart failure. Although this change is usually associated with large infarcts, some patients with relatively small infarcts have adverse remodeling, whereas other patients with larger infarcts (who survive the first several days after AMI) do not. This paper reviews the relevant data supporting the hypothesis that individual differences in the intensity of the post-AMI inflammatory response, involving 1 or more inflammatory-modulating pathways, may contribute to adverse LV remodeling. It concludes by outlining how individual variations in the inflammatory response could provide important novel therapeutic targets and strategies.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American College of Cardiology - Volume 67, Issue 17, 3 May 2016, Pages 2050-2060
نویسندگان
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