کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5985262 | 1178773 | 2016 | 8 صفحه PDF | دانلود رایگان |
- We looked at the prevalence of abnormal non-HDL-Cholesterol and triglycerides and their correlates among Lebanese school children.
- We found that the respective prevalence of high non-HDL-Cholesterol and triglycerides was of 9.2% and 26.6%.
- Obesity, gender, age, socioeconomic status, testosterone levels in boys are the main explanatory factors of lipid parameters.
BackgroundThe prevalence of dyslipidelmia in pediatric Middle-Eastern populations is unknown. Our study aims to investigate the distribution and correlates of non-high-density lipoprotein cholesterol (non-HDL-C) and triglycerides among Lebanese school children.MethodsA total of 969 subjects aged 8-18Â years were included in the study (505 boys and 464 girls). Recruitment was done from 10 schools located in the Great Beirut and Mount-Lebanon areas. Non-fasting total cholesterol, triglycerides, and HDL-cholesterol (HDL-C) were measured. Non-HDL-C was calculated. Schools were categorized into 3 socioeconomic statuses (SESs; low, middle, and high).ResultsIn the overall population, the prevalence of high non-HDL-C (>3.8Â mmol/L), very high non-HDL-C (>4.9Â mmol/L), and high triglycerides (>1.5Â mmol/l) are respectively 9.2%, 1.24%, and 26.6%. There is no significant gender difference for non-HDL-C or triglycerides. Non-HDL-C and triglycerides are inversely correlated with age in girls (PÂ <Â .0001 for both variables) but not in boys. They are also positively correlated with body mass index (BMI) in boys and girls (PÂ <Â .0001 for all variables). There is no relationship between schools' socioeconomic process (SES) and non-HDL-C. However, triglycerides are higher in children from lower SES schools. After adjustment for age and body mass index (BMI), testosterone is inversely associated with triglycerides in boys (PÂ <Â .0001). In a multivariate regression analysis, non-HDL-C is independently associated with age and BMI in girls (PÂ <Â .0001 for both variables) but only with BMI in boys (PÂ <Â .0001), whereas triglycerides are independently associated with BMI and schools' SES in both girls and boys.ConclusionsThis study confirms, in our population, the association between obesity and both high non-HDL-C and triglycerides, and between high triglycerides and low SES.
Journal: Journal of Clinical Lipidology - Volume 10, Issue 2, MarchâApril 2016, Pages 378-385