کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
600477 1454303 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
TiO2 nanorods via one-step electrospinning technique: A novel nanomatrix for mouse myoblasts adhesion and propagation
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی شیمی کلوئیدی و سطحی
پیش نمایش صفحه اول مقاله
TiO2 nanorods via one-step electrospinning technique: A novel nanomatrix for mouse myoblasts adhesion and propagation
چکیده انگلیسی

This study was aimed at the synthesis and characterization of novel Titania nanorods by sol–gel electrospinning technique. The physicochemical properties of the synthesized nanorods were determined by field emission scanning electron microscopy (FE-SEM), energy dispersive X-ray spectroscopy (EDX), transmission electron microscopy (TEM), and X-ray diffraction (XRD) pattern. To examine the in vitro cytotoxicity, mouse myoblast C2C12 cells were treated with different concentrations of as prepared TiO2 nanorods and the viability of cells was analyzed by Cell Counting Kit-8 assay at regular time intervals. The morphological features of the cells attached with nanorods were examined by Bio-SEM. Cytotoxicity experiments indicated that the mouse myoblast cells could attach to the TiO2 nanorods after being cultured. We observed that TiO2 nanorods could support cell adhesion and growth and guide spreading behavior of myoblasts. We conclude that the electrospun TiO2 nanorods scaffolds with unique morphology had excellent biocompatibility. Thus, the current work demonstrates that the as-synthesized TiO2 nanorods represent a promising biomaterial to be exploited for various tissue engineering applications.

Figure optionsDownload as PowerPoint slideHighlights
► Synthesis and characterization of novel TiO2 nanorods by electrospinning.
► The attachment and proliferation of myoblasts on the TiO2 were assayed by in vitro cell compatibility test.
► TiO2 nanorods signify a promising biomaterial for tissue engineering applications.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Colloids and Surfaces B: Biointerfaces - Volume 101, 1 January 2013, Pages 424–429
نویسندگان
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