Gels of Pluronic F127 and nonionic surfactants from rheological characterization to controlled drug permeation

► Hydrophilic drug entrapment in amphiphilic biocompatible polymer network. ► Association between Pluronic F127 and nonionic surfactant Tween 60. ► Thermal gelation of pluronic-vesicle system. ► Dependence of the polymer network on the drug release.