Study of zwitterionic sulfopropylbetaine containing reactive siloxanes for application in antibacterial materials

► The SSPB contains both QACs and reactive siloxane for durable antibacterial materials. ► The SSPB has good antibacterial activity with MIC of 70 μmol/ml and broad pH application range. ► The SSPB modified glass surface shows durable antibacterial activity. ► The antibacterial mechanism of SSPB may be bacteriostasis, but not bactericidal mechanism. ► The SSPB show no skin stimulation and nontoxic to animals.