کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6012736 1185906 2013 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A critical evaluation of the lateralizing significance of material-specific memory deficits in patients with mesial temporal lobe epilepsy with hippocampal sclerosis
ترجمه فارسی عنوان
ارزیابی انتقادی از اهمیت جانبی کمبود حافظه خاص در بیماران مبتلا به صرع لوب مرییی اسکلروز با اسکلروز هیپوکمپ
کلمات کلیدی
اسکلروز هیپوکمپ، حافظه خاصی از مواد، اختلال عملکرد عصب شناختی، صرع لوب صرع، حافظه کلامی، حافظه بصری،
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی


- Assessed the lateralizing value of material-specific memory deficits in patients with MTLE-HS preoperatively
- Compared with controls, patients with MTLE-HS performed poorly on intelligence and memory tests.
- Learning trials and delayed recall were the only tests associated with left MTLE-HS.
- Prior to surgery, material-specific memory deficits are of limited value in lateralizing temporal lobe dysfunction.

To critically assess the value of material-specific memory deficits in lateralizing temporal lobe dysfunction preoperatively, we compared the neuropsychological data of 50 consecutive patients with unilateral mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS; right: 31, left: 19) with those of 50 age- and education-matched healthy control subjects. On case-control comparison, both the subcohorts with left and right MTLE-HS performed poorly on intelligence tests, in addition to individual memory tests. However, comparison of the verbal and visual memory functions between subcohorts with right and left MTLE-HS revealed that learning trials and delayed word list recall were the only tests that hypothesized left temporal lobe dysfunction. We conclude that material-specific memory deficits are largely test driven, but there is a lateralizing role for task-specific deficits in left MTLE-HS. Although neuropsychological data help to define baseline neuropsychological impairment, caution should be exercised in interpreting the lateralizing value of material-specific memory deficits prior to surgery.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Epilepsy & Behavior - Volume 28, Issue 3, September 2013, Pages 460-466
نویسندگان
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