کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6014004 | 1185927 | 2011 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Cognitive effects of carisbamate in randomized, placebo-controlled, healthy-volunteer, multidose studies
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Cognitive effects of carisbamate in randomized, placebo-controlled, healthy-volunteer, multidose studies Cognitive effects of carisbamate in randomized, placebo-controlled, healthy-volunteer, multidose studies](/preview/png/6014004.png)
چکیده انگلیسی
⺠Carisbamate is a novel drug in development for treatment of seizures and neuropathic pain. ⺠Three controlled, multiple-dose, phase I crossover studies were conducted. ⺠Cognitive effects were assessed in healthy volunteers treated for 5-9 days. ⺠No clinically significant adverse cognitive effects were observed at doses < 1000 mg/day. ⺠Effects were mild to modest at the higher doses tested.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Epilepsy & Behavior - Volume 22, Issue 2, October 2011, Pages 324-330
Journal: Epilepsy & Behavior - Volume 22, Issue 2, October 2011, Pages 324-330
نویسندگان
Kimford J. Meador, H.R. Brashear, Frank Wiegand, Peter Zannikos, Gerald Novak,