Neuropsychological performance and seizure-related risk factors in patients with temporal lobe epilepsy: A retrospective cross-sectional study

► Cognitive impairment in multiple domains is evident in most patients with temporal lobe epilepsy. ► Age at seizure onset is the strongest predictor of intellectual impairment. ► Seizure frequency and number of antiepileptic drugs used significantly predict cognitive deficits. ► Epilepsy duration is a less potent predictor of cognitive deficits.