What is the role of depressive symptoms among other predictors of quality of life in people with well-controlled epilepsy on monotherapy?

► One-fifth of patients with well-controlled epilepsy on monotherapy had depression symptoms. ► Adverse events of antiepileptic drugs were manifested by 58.7% of those patients. ► Depressed patients were more likely to report adverse events than non-depressed patients. ► The major predictor of quality of life was depression symptoms, followed by adverse events of antiepileptic drugs.