Role of cortical reorganization on the effect of 5-HT pharmacotherapy for spinal cord injury

► Effect of 5-HT agonists on functional recovery is related to cortical reorganization after spinal cord injury ► mCPP + animal take more weight supported steps after mCPP administration compared to mCPP − animals ► Neurons recorded from mCPP + animals were more responsive to passive sensory stimulation while lightly anesthetized ► Neurons recorded from mCPP + animals were more responsive to active sensorimotor stimulation during treadmill locomotion compare