Pink1-deficiency in mice impairs gait, olfaction and serotonergic innervation of the olfactory bulb

►Pink1 deficient animals show olfactory impairments. ►Aged Pink1 deficient animals exhibit gait alterations. ►Aged Pink1 deficient animals exhibit alterations in the serotonergic system. ►Mitochondrial fragmentation induced by acute loss of Pink1 is compensated over time. ►Pink1 deficient mice are models for early phases of Parkinson's Disease.