A re-assessment of a combinatorial treatment involving Schwann cell transplants and elevation of cyclic AMP on recovery of motor function following thoracic spinal cord injury in rats

► A previous report of a potential therapy for SCI is not confirmed. ► Combinatorial treatments are not reliably more efficacious than single treatments. ► A failure to confirm raises doubts about translatability of basic discoveries. ► Methods sections in many journals do not provide sufficient detail for replication.