Altered expression of brain monocarboxylate transporter 1 in models of temporal lobe epilepsy

► Alterations in brain MCT1 are present in human temporal lobe epilepsy (TLE). ► Similar alterations have now been found in three animal models of TLE. ► These findings suggest a key role of MCT1 in the pathophysiology of TLE. ► The exact role of MCT1 in TLE can now be tested in relevant animal models.