Preferential accumulation of amyloid-beta in presynaptic glutamatergic terminals (VGluT1 and VGluT2) in Alzheimer's disease cortex

► We quantify glutamatergic terminals in Alzheimer's disease and aged control brain. ► Glutamatergic boutons are fairly abundant in pathologic and aged control cortex. ► We examine levels of Abeta in glutamatergic boutons in Alzheimer's disease cortex. ► High levels of Abeta are found in excitatory boutons in Alzheimer's disease cortex.