Ferritin overexpression in Drosophila glia leads to iron deposition in the optic lobes and late-onset behavioral defects

► Ferritin overexpression in Drosophila glia causes a late onset movement disorder. ► Ferritin overexpression in Drosophila glia disrupts circadian rhythms in aging flies. ► Transgenic expression of both ferritin subunits is required for ferritin assembly. ► Ferritin forms crystalline iron-loaded inclusions specifically in optic lobe glia.