Overexpression of glia maturation factor reinstates susceptibility to myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in glia maturation factor deficient mice

►Efficient and sustained adenoviral-mediated expression of GMF in CNS of mice ►Adenoviral-mediated expression of GMF in mice exacerbates MOG-induced EAE ►Reintroduction of GMF in GMF-KO mice increases susceptibility to MOG-induced EAE