Adhesion molecules as potential targets for neuroprotection in a rodent model of Parkinson's disease

► Levels of adhesion molecules are altered in a rodent model of Parkinson's disease. ► Peripheral inflammatory stimuli modulate expression of selected adhesion molecules. ► Peripheral inflammatory stimuli reduce toxin-induced loss of dopaminergic neurons. ► Manipulation of peripheral immune status can slow down Parkinson's disease progression.