کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6027683 | 1580917 | 2014 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Diffusion properties of major white matter tracts in young, typically developing children
ترجمه فارسی عنوان
خواص توزیع مواد اصلی ماده سفید در کودکان جوان، به طور معمول در حال توسعه
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کلمات کلیدی
فرزندان، ماده سفید، تراکتوری، توسعه، تفاوت های جنسی، کمال گرایی،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب شناختی
چکیده انگلیسی
Brain development occurs rapidly during the first few years of life involving region-specific changes in both gray matter and white matter. Due to the inherent difficulties in acquiring magnetic resonance imaging data in young children, little is known about the properties of white matter in typically developing toddlers. In the context of an ongoing study of young children with autism spectrum disorder, we collected diffusion-weighted imaging data during natural nocturnal sleep in a sample of young (mean age = 35 months) typically developing male and female (n = 41 and 25, respectively) children. Axial diffusivity, radial diffusivity, mean diffusivity and fractional anisotropy were measured at 99 points along the length of 18 major brain tracts. Influences of hemisphere, age, sex, and handedness were examined. We find that diffusion properties vary significantly along the length of the majority of tracks. We also identify hemispheric and sex differences in diffusion properties in several tracts. Finally, we find the relationship between age and diffusion parameters changes along the tract length illustrating variability in age-related white-matter development at the tract level.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: NeuroImage - Volume 88, March 2014, Pages 143-154
Journal: NeuroImage - Volume 88, March 2014, Pages 143-154
نویسندگان
Ryan T. Johnson, Jason D. Yeatman, Brian A. Wandell, Michael H. Buonocore, David G. Amaral, Christine Wu Nordahl,