5-HT1A sex based differences in Bmax, in vivo KD, and BPND in the nonhuman primate

These results suggest that the higher BPND values found in females are the result of lower [18F]mefway KDapp. Although a more experimentally complex measurement, separate assay of KDapp and Bmax provides a more sensitive measure than BPND to identify the underlying differences between females and males in 5-HT1A function.