کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
603290 880204 2011 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Interactions of amphiphilic block copolymers with lipid model membranes
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی شیمی کلوئیدی و سطحی
پیش نمایش صفحه اول مقاله
Interactions of amphiphilic block copolymers with lipid model membranes
چکیده انگلیسی

Studies on interactions between amphiphilic block copolymers and lipid membranes have been focused traditionally on ABA triblock copolymers of poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide), widely due to their commercial availability. However, new architectures of amphiphilic block copolymer have been synthesized in recent years partially taking advantage of new polymerization techniques. This review focuses on amphiphilic block copolymers with potential biological activity and on model membrane systems used for studying interactions with such block copolymers. Experimental methods to study block copolymer–phospholipid interactions in Langmuir monolayers, liposomes, and planar bilayers are summarized. This work is intended to convey a better understanding of amphiphilic block copolymers used for in vitro and in vivo experiments in medicine and pharmacy. Recent developments and open questions are addressed.

Figure optionsDownload high-quality image (332 K)Download as PowerPoint slideHighlights
► Interactions of amphiphilic block copolymers with model membranes.
► Novel polymer architectures through new polymerization pathways.
► Huge potential for pharmaceutical and biomedical applications.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Colloid & Interface Science - Volume 16, Issue 6, December 2011, Pages 491–498
نویسندگان
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