Atlas-based investigation of human brain tissue microstructural spatial heterogeneity and interplay between transverse relaxation time and radial diffusivity

► A FreeSurfer-based qMRI Atlas of T2 relaxation and DTI metrics is presented. ► The qMRI atlas spatial heterogeneity is analyzed on right-handed controls. ► The qMRI atlas is used to examine the interplay between T2 and RD. ► We examined benchmark structures such as the CC, hippocampus and putamen. ► Our results will help interpret MRI metrics in terms of biophysical contributors.