Prognostic Value of O-(2-[18F]-Fluoroethyl)-L-Tyrosine-Positron Emission Tomography Imaging for Histopathologic Characteristics and Progression-Free Survival in Patients with Low-Grade Glioma

We found that 78.5% of low-grade gliomas do show elevated tracer uptake in 18F-FET-PET imaging. Low-grade glioma without tracer uptake exclude oligodendroglial differentiation and 1p19q codeletion. Further differentiation between molecular subtypes is not possible with static 18F-FET-PET. No correlation of progression-free survival to tracer uptake and IDH1/2-mutation status was observed.