Combined Use of a Gasket Seal Closure and a Vascularized Pedicle Nasoseptal Flap Multilayered Reconstruction Technique for High-Flow Cerebrospinal Fluid Leaks After Endonasal Endoscopic Skull Base Surgery

The combined use of a gasket seal closure and a VP-NSF multilayered reconstruction technique for high-flow CSF leaks after endonasal endoscopic skull base surgery may significantly reduce the rates of postoperative CSF leaks and intracranial infections. Lumbar drainage after the operation is a necessary auxiliary method.