کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6054914 1198761 2015 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Do high-risk human papillomaviruses cause oral cavity squamous cell carcinoma?
ترجمه فارسی عنوان
آیا پاپیلومایویروس های با خطر بالا باعث ایجاد کارسینوم سلول سنگفرشی می شوند؟
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
چکیده انگلیسی
High-risk human papillomaviruses (HR-HPV) are an established etiologic factor for a growing number of oropharyngeal cancers. However, their potential role in other upper aerodigestive tract locations is still a matter of debate, particularly in the oral cavity. This is of paramount importance as in the future diagnosis, treatment and follow up in head and neck squamous cell carcinoma may vary according to HPV status. This article reviews the recent published data and highlights some of the pitfalls that have hampered the accurate assessment of HR-HPV oncological role outside the oropharynx. We demonstrate that, in contrast to the oropharynx, only a small fraction of cancers located in the oral cavity seem to be HPV-related even in young non-smoking non-drinking patients. We emphasize several relevant factors to consider in assumed HPV-induced oral cavity cancers and discuss the current theories that explain why HPV-induced cancers arise preferentially in the oropharynx.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Oncology - Volume 51, Issue 3, March 2015, Pages 229-236
نویسندگان
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